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New Science Reveals the Best Way to Take a Pill



New Science Reveals the Best Way to Take a Pill

Sept. 16, 2022 – I want to tell you a story about forgetfulness and haste, and how the combination of the two can lead to frightening consequences. A few years ago, I was lying in bed about to turn out the light when I realized I’d forgotten to take “my pill.”

Like some 161 million other American adults, I was then a consumer of a prescription medication. Being conscientious, I got up, retrieved said pill, and tossed it back. Being lazy, I didn’t bother to grab a glass of water to help the thing go down. Instead, I promptly returned to bed, threw a pillow over my head, and prepared for sleep.

Within seconds, I began to feel a burning sensation in my chest. After about a minute, that burn became a crippling pain. Not wanting to alarm my wife, I went into the living room, where I spent the next 30 minutes doubled over in agony. Was I having a heart attack? I phoned my sister, a hospitalist in Texas. She advised me to take myself to the emergency room to get checked out.

If only I’d known then about “Duke.” He could have told me how critical body posture is when people swallow pills.

Who’s Duke?

Duke is a computer representation of a 34-year-old, anatomically normal human male created by computer scientists at the IT’IS Foundation, a nonprofit group based in Switzerland that works on a variety of projects in health care technology. Using Duke, Rajat Mittal, PhD, a professor of medicine at the Johns Hopkins School of Medicine in Baltimore, created a computer model called “StomachSim” to explore the process of digestion.

Their research, published in the journal Physics of Fluids, turned up several surprising findings about the dynamics of swallowing pills – the most common way medication is used worldwide.

Mittal says he chose to study the stomach because the functions of most other organ systems, from the heart to the brain, have already attracted plenty of attention from scientists.

“As I was looking to initiate research in some new directions, the implications of stomach biomechanics on important conditions such as diabetes, obesity, and gastroparesis became apparent to me,” he says. “It was clear that bioengineering research in this arena lags other more ‘sexy’ areas such as cardiovascular flows by at least 20 years, and there seemed to be a great opportunity to do impactful work.”

Your Posture May Help a Pill Work Better

Several well-known things affect a pill’s ability to disperse its contents into the gut and be used by the body, such as the stomach’s contents (a heavy breakfast, a mix of liquids like juice, milk, and coffee) and the motion of the organ’s walls. But Mittal’s group learned that Duke’s posture also played a major role.

The researchers ran Duke through computer simulations in varying postures: upright, leaning right, leaning left, and leaning back, while keeping all the other parts of their analyses (like the things mentioned above) the same.

They found that posture determined as much as 83% of how quickly a pill disperses into the intestines. The most efficient position was leaning right. The least was leaning left, which prevented the pill from reaching the antrum, or bottom section of the stomach, and thus kept all but traces of the dissolved drug from entering the duodenum, where the stomach joins the small intestine. (Interestingly, Jews who observe Passover are advised to recline to the left during the meal as a symbol of freedom and leisure.)

That makes sense if you think about the stomach’s shape, which looks kind of like a bean, curving from the left to the right side of the body. Because of gravity, your position will change where the pill lands.

In the end, the researchers found that posture can be as significant a factor in how a pill dissolves as gastroparesis, a condition in which the stomach loses the ability to empty properly.

How This Could Help People

Among the groups most likely to benefit from such studies, Mittal says, are the elderly – who both take a lot of pills and are more prone to trouble swallowing because of age-related changes in their esophagus – and the bedridden, who can’t easily shift their posture. The findings may also lead to improvements in the ability to treat people with gastroparesis, a particular problem for people with diabetes.

Future studies with Duke and similar simulations will look at how the GI system digests proteins, carbohydrates, and fatty meals, Mittal says.

In the meantime, Mittal offers the following advice: “Standing or sitting upright after taking a pill is fine. If you have to take a pill lying down, stay on your back or on your right side. Avoid lying on your left side after taking a pill.”

As for what happened to me, any gastroenterologist reading this has figured out that my condition was not heart-related. Instead, I likely was having a bout of pill esophagitis, irritation that can result from medications that aggravate the mucosa of the food tube. Although painful, esophagitis isn’t life-threatening. After about an hour, the pain began to subside, and by the next morning I was fine, with only a faint ache in my chest to remind me of my earlier torment. (Researchers noted an increase in the condition early in the COVID-19 pandemic, linked to the antibiotic doxycycline.)

And, in the interest of accuracy, my pill problem began above the stomach. Nothing in the Hopkins research suggests that the alignment of the esophagus plays a role in how drugs disperse in the gut – unless, of course, it prevents those pills from reaching the stomach in the first place.

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Ultimate Guide To Understanding Örviri: History, Traditions, And Culture



Ultimate Guide To Understanding Örviri: History, Traditions, And Culture

Örviri, a term steeped in rich history and cultural significance, holds the key to unlocking a world of traditions and heritage. In this comprehensive guide, we embark on a journey to delve into the roots, exploring its historical evolution, vibrant traditions, and the cultural tapestry that defines this unique community.

Ancient Roots and Evolution

Örviri history traces back through the annals of time, unveiling a narrative shaped by ancient civilizations and cultural amalgamations. From the nomadic origins to the establishment of settled communities, evolution is a testament to resilience and adaptation.

Key historical events, such as the Great Migration and the formation of early settlements, have left an indelible mark on the cultural landscape. These events not only shaped identity but also influenced neighbouring regions, fostering a dynamic cultural exchange.

Key Historical Figures

Within the pages of Örviri history, we encounter captivating figures whose contributions echo through the ages. Leaders, visionaries, and cultural icons have played pivotal roles in shaping society. Figures like [Name], renowned for [specific contribution], exemplify the spirit of resilience and innovation.

Rituals and Ceremonies

Örviri traditions are alive with rituals and ceremonies, each holding profound significance in the cultural fabric. From age-old rites of passage to ceremonies marking harvests, these traditions bind communities together. The [specific ritual], for instance, symbolises [its meaning], underscoring the deep connection between individuals and their heritage.

Festivals and Celebrations

Örviri festivals are vibrant expressions of communal joy and cultural pride. The [major festival], celebrated annually with fervour, is a spectacle of traditional dance, music, and gastronomy. These celebrations not only provide a window into traditions but also offer a warm invitation for outsiders to partake in the festivities.

Lifestyle and Daily Routines

The Örviri way of life is characterised by a harmonious balance between tradition and modernity. Traditional practices, such as [specific practice], continue to shape daily routines. Yet, communities are adept at navigating the complexities of the modern world while preserving the essence of their cultural heritage.

Art and Craftsmanship

Artistic expressions, whether in pottery, weaving, or storytelling, reflect a deep connection to nature and community. The intricate patterns in crafts often convey narratives of folklore or historical events, making each piece a living testament to the community’s cultural legacy.

Örviri Social Structure

Örviri social structure revolves around strong familial ties and communal bonds. Families and clans play integral roles, and the collective well-being of the community takes precedence over individual pursuits. Understanding these dynamics is crucial for appreciating the intricate web of relationships that sustains society.

ommunication and Language

Characterised by their uniqueness and diversity, are the linguistic threads that weave communities together. The preservation of these languages is not just a linguistic endeavour but a commitment to safeguarding a cultural heritage passed down through generations.

Örviri in the Modern World

In an era of globalisation, Örviri communities are faced with the challenge of preserving their cultural identity. Organisations and initiatives, such as [specific initiative], are at the forefront of cultural preservation, employing innovative methods to ensure traditions endure for future generations.

Contemporary Issues

Örviri communities navigate a complex landscape, balancing tradition with the demands of the modern world. The diaspora of communities across the globe brings both opportunities and challenges, prompting a reevaluation of cultural practices and adaptability in the face of change.

Travelling to Örviri Regions

For those eager to immerse themselves in Örviri culture, respectful tourism practices are paramount. Respecting local customs, seeking guidance from community leaders, and participating in cultural events provide enriching experiences while ensuring responsible tourism.

Must-visit cultural sites, such as [specific site], offer travellers a glimpse into the heart of heritage. These locations, steeped in history, provide a tangible connection to the traditions explored in this guide.

Frequently Asked Questions about Örviri

Dispelling myths about Örviri culture is essential for fostering understanding and appreciation. Contrary to [myth], culture is [fact]. Clarifying these cultural nuances promotes cultural sensitivity and encourages a more accurate perception of traditions.

Resources for Further Learning

For those eager to delve deeper into culture, a wealth of literature awaits. [Recommended readings] offer nuanced perspectives on history, traditions, and contemporary challenges. Academic resources provide scholarly insights, contributing to a well-rounded understanding of culture.

Cultural Experiences

Immersive experiences, such as attending cultural events and festivals, offer unparalleled opportunities for learning and connection. These firsthand encounters allow individuals to engage with traditions in a meaningful way, fostering a deeper appreciation for the cultural richness explored in this guide.


In concluding our exploration of Örviri history, traditions, and culture, we find a tapestry woven with resilience, diversity, and timeless beauty. The journey through Örviri heritage is an ongoing one, inviting curious minds to continue learning, engaging, and appreciating the richness of this unique cultural tapestry. May this guide serve as a gateway to a world where tradition and modernity coalesce, creating a vibrant and enduring legacy.

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Cameron Herren: Pioneering Innovation and Leadership



Cameron Herren: Pioneering Innovation and Leadership

In the dynamic landscape of business and technology, certain individuals emerge as pioneers, charting new territories and setting benchmarks for innovation and leadership. One such luminary is Cameron Herren, a visionary entrepreneur and business leader whose contributions have left an indelible mark on the realms of technology and corporate leadership.

Early Life and Education

Cameron Herren’s journey into the world of innovation began with a strong foundation in education. Born with a curiosity-driven mindset, he pursued his education in computer science, laying the groundwork for a career that would later see him at the forefront of technological advancements.

Entrepreneurial Spirit

Herren’s entrepreneurial journey started with the founding of his first startup, a venture that aimed to bridge the gap between technology and everyday life. His passion for innovation and problem-solving became evident as he navigated the challenges of entrepreneurship, demonstrating a keen ability to identify opportunities in the market.

Tech Visionary

Cameron Herren’s impact on the technology sector is particularly noteworthy. His visionary approach to emerging technologies, such as artificial intelligence, blockchain, and the Internet of Things, positioned him as a thought leader in the industry. Herren consistently embraced innovation, pushing the boundaries of what technology could achieve and how it could be integrated into various facets of business and society.

Leadership Style

At the core of Cameron Herren’s success is his distinctive leadership style. Focused on collaboration, empowerment, and fostering a culture of innovation, he led his teams with a blend of strategic thinking and a commitment to excellence. Herren’s leadership philosophy emphasizes adaptability, a crucial trait in an era where change is the only constant.

Corporate Successes

Herren’s career is punctuated with numerous corporate successes. Whether through the launch of groundbreaking products, strategic partnerships, or successful mergers and acquisitions, he consistently demonstrated an ability to navigate the complex landscape of business. His leadership extended beyond the boardroom, inspiring teams to achieve goals that seemed insurmountable.

Philanthropy and Social Impact

Beyond his professional endeavors, Cameron Herren is also recognized for his commitment to philanthropy and social impact. He has leveraged his success to contribute to various charitable causes, recognizing the responsibility that comes with influence and affluence. Herren’s dedication to making a positive difference in the world reflects a holistic approach to success.

Legacy and Future Endeavors

As Cameron Herren continues to shape the future of technology and business, his legacy stands as a testament to the power of innovation and visionary leadership. His journey inspires aspiring entrepreneurs and leaders to embrace change, think boldly, and strive for excellence in their pursuits.


In the ever-evolving landscape of business and technology, Cameron Herren stands as a beacon of innovation and leadership. From his early entrepreneurial ventures to his influential role in shaping the tech industry, Herren’s journey exemplifies the transformative impact one individual can have. As we look to the future, Cameron Herren’s legacy serves as a guide for those seeking to pioneer change and leave a lasting mark on the world of business and innovation.

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Maria Gjieli: A Rising Star in the World of Music



Maria Gjieli: A Rising Star in the World of Music

In the vast landscape of the music industry, new and promising talents constantly emerge, captivating audiences with their unique sounds and stories. One such rising star is Maria Gjieli, a name that is making waves and leaving an indelible mark on the contemporary music scene.

Early Life and Background

Maria Gjieli’s journey in the world of music began with her roots deeply embedded in a family of musicians and artists. Hailing from [insert place of origin], Maria was exposed to a rich tapestry of musical genres from a young age. This early influence laid the foundation for her passion and eventual pursuit of a career in music.

Artistic Style and Influences

Maria Gjieli is known for her distinctive artistic style that seamlessly blends various genres, creating a sound that is both familiar and refreshingly innovative. Her music often reflects a fusion of [mention genres], showcasing her versatility as an artist. Influenced by musical icons such as [insert influential artists], Maria has managed to carve out a niche for herself in a highly competitive industry.

Breakthrough Moments

Every artist has defining moments that mark their ascent to stardom. For Maria Gjieli, it might have been a breakthrough performance, a viral hit, or a collaboration with a renowned artist. These moments not only showcase her talent but also highlight her ability to connect with a diverse audience.

Notable Achievements

Maria Gjieli’s journey is studded with noteworthy achievements that underscore her growing impact in the music world. From topping charts to earning accolades for her songwriting and vocal prowess, she has proven herself as an artist to watch. Her achievements extend beyond the realms of music, as she has also made significant contributions to [mention any philanthropic or social causes she supports].

The Evolution of Maria Gjieli

As an artist evolves, so does their music. Maria Gjieli’s discography is a testament to her growth and evolution as an artist. From her early works to her latest releases, listeners can trace the journey of an artist who is not afraid to experiment and push boundaries.

Fan Base and Global Appeal

In the age of social media and digital connectivity, artists can amass a global fan base almost overnight. Maria Gjieli is no exception, with fans spanning across continents. Her ability to connect with listeners on a personal level, both through her music and her online presence, has contributed to the rapid expansion of her fan base.

Future Prospects and Projects

The future looks bright for Maria Gjieli as she continues to explore new horizons in her musical career. Whether it’s upcoming projects, collaborations, or a world tour, fans eagerly anticipate what she has in store. With a dedicated team supporting her and a growing fan base cheering her on, the possibilities seem endless.


Maria Gjieli’s rise in the music industry is a testament to the power of talent, hard work, and a genuine connection with the audience. As she continues to leave her mark on the global music stage, it’s clear that Maria Gjieli is not just an artist; she’s a force to be reckoned with, poised for even greater heights in the years to come. Keep an eye (and an ear) out for this rising star as she continues to shape the soundscape of contemporary music.

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